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Preferential binding of fullerene and fullerenol with the N-terminal and middle regions of amyloid beta peptide: an in silico investigation

Amyloid beta (Aβ) deposits are implicated in the pathogenesis of debilitating neurodegenerative disorders such as Alzheimer’s disease. In the present study, the interactions of carbon-based nanoparticles (NPs) such as fullerene and fullerenol having different surface chemistry with Aβ were investiga...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Pandya, Vishal, Baweja, Lokesh, Dhawan, Alok
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863620/
https://ncbi.nlm.nih.gov/pubmed/29593399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125011
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