Llwytho...

Distinct Binding Dynamics, Sites and Interactions of Fullerene and Fullerenols with Amyloid-β Peptides Revealed by Molecular Dynamics Simulations

The pathology Alzheimer’s disease (AD) is associated with the self-assembly of amyloid-β (Aβ) peptides into β-sheet enriched fibrillar aggregates. A promising treatment strategy is focused on the inhibition of amyloid fibrillization of Aβ peptide. Fullerene C(60) is proved to effectively inhibit Aβ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Liu, Zhiwei, Zou, Yu, Zhang, Qingwen, Chen, Peijie, Liu, Yu, Qian, Zhenyu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514889/
https://ncbi.nlm.nih.gov/pubmed/31027286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20082048
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