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Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines

The functional relevancy of mutations occurring in the regulatory regions in cancers remains mostly elusive. Here, we identified and analyzed regulatory mutations having transcriptional consequences in lung adenocarcinoma-derived cell lines. We phased the mutations in the regulatory regions to the d...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Sereewattanawoot, Sarun, Suzuki, Ayako, Seki, Masahide, Sakamoto, Yoshitaka, Kohno, Takashi, Sugano, Sumio, Tsuchihara, Katsuya, Suzuki, Yutaka
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862974/
https://ncbi.nlm.nih.gov/pubmed/29563587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23342-1
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