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Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines

The functional relevancy of mutations occurring in the regulatory regions in cancers remains mostly elusive. Here, we identified and analyzed regulatory mutations having transcriptional consequences in lung adenocarcinoma-derived cell lines. We phased the mutations in the regulatory regions to the d...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sereewattanawoot, Sarun, Suzuki, Ayako, Seki, Masahide, Sakamoto, Yoshitaka, Kohno, Takashi, Sugano, Sumio, Tsuchihara, Katsuya, Suzuki, Yutaka
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862974/
https://ncbi.nlm.nih.gov/pubmed/29563587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23342-1
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