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Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines

The functional relevancy of mutations occurring in the regulatory regions in cancers remains mostly elusive. Here, we identified and analyzed regulatory mutations having transcriptional consequences in lung adenocarcinoma-derived cell lines. We phased the mutations in the regulatory regions to the d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sereewattanawoot, Sarun, Suzuki, Ayako, Seki, Masahide, Sakamoto, Yoshitaka, Kohno, Takashi, Sugano, Sumio, Tsuchihara, Katsuya, Suzuki, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862974/
https://ncbi.nlm.nih.gov/pubmed/29563587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23342-1
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