Empirical Null Estimation using Zero-inflated Discrete Mixture Distributions and its Application to Protein Domain Data

In recent mutation studies, analyses based on protein domain positions are gaining popularity over gene-centric approaches since the latter have limitations in considering the functional context that the position of the mutation provides. This presents a large-scale simultaneous inference problem, w...

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Vydáno v:Biometrics
Hlavní autoři: Gauran, Iris Ivy M., Park, Junyong, Lim, Johan, Park, DoHwan, Zylstra, John, Peterson, Thomas, Kann, Maricel, Spouge, John L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862774/
https://ncbi.nlm.nih.gov/pubmed/28940296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12779
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