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Prolonged in vivo expression and anti-tumor response of DNA-based anti-HER2 antibodies
Antibody gene transfer presents an appealing alternative to conventional antibody protein therapy. This pre-clinical study evaluates the impact of various parameters on the pharmacokinetics and efficacy of in vivo expressed DNA-based anti-HER2 monoclonal antibodies (mAbs), newly engineered and deliv...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5862603/ https://ncbi.nlm.nih.gov/pubmed/29568382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24426 |
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