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DNA-Based Delivery of Checkpoint Inhibitors in Muscle and Tumor Enables Long-Term Responses with Distinct Exposure
Checkpoint-inhibiting antibodies elicit impressive clinical responses, but still face several issues. The current study evaluated whether DNA-based delivery can broaden the application of checkpoint inhibitors, specifically by pursuing cost-efficient in vivo production, facilitating combination ther...
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| Wydane w: | Mol Ther |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Gene & Cell Therapy
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7132619/ https://ncbi.nlm.nih.gov/pubmed/32101701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.02.007 |
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