Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression

Trifluridine/tipiracil (FTD/TPI or TFTD, also known as TAS-102) is a combination of the antineoplastic thymidine analog, FTD, and thymidine phosphorylase inhibitor, TPI (molar ratio 1:0.5). FTD/TPI was approved in Japan, the United States, and the European Union for the treatment of unresectable adv...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Matsuoka, Kazuaki, Nakagawa, Fumio, Kobunai, Takashi, Takechi, Teiji
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862589/
https://ncbi.nlm.nih.gov/pubmed/29568368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24412
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