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Synergistic anticancer activity of a novel oral chemotherapeutic agent containing trifluridine and tipiracil in combination with anti-PD-1 blockade in microsatellite stable-type murine colorectal cancer cells

Trifluridine/tipiracil (FTD/TPI) is a combination of FTD, an antineoplastic thymidine-based nucleoside analog, and TPI, which acts to enhance the bioavailability of FTD in vivo. It is used to treat patients with unresectable advanced or recurrent colorectal cancer that is refractory to standard ther...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Suzuki, Norihiko, Tsukihara, Hiroshi, Nakagawa, Fumio, Kobunai, Takashi, Takechi, Teiji
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665850/
https://ncbi.nlm.nih.gov/pubmed/29119052
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