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Development and validation of a physiology-based model for the prediction of pharmacokinetics/toxicokinetics in rabbits

The environmental fates of pharmaceuticals and the effects of crop protection products on non-target species are subjects that are undergoing intense review. Since measuring the concentrations and effects of xenobiotics on all affected species under all conceivable scenarios is not feasible, standar...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Mavroudis, Panteleimon D., Hermes, Helen E., Teutonico, Donato, Preuss, Thomas G., Schneckener, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862475/
https://ncbi.nlm.nih.gov/pubmed/29561908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194294
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