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Indel detection from RNA-seq data: tool evaluation and strategies for accurate detection of actionable mutations
Driver somatic mutations are a hallmark of a tumor that can be used for diagnosis and targeted therapy. Mutations are primarily detected from tumor DNA. As dynamic molecules of gene activities, transcriptome profiling by RNA sequence (RNA-seq) is becoming increasingly popular, which not only measure...
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| Published in: | Brief Bioinform |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5862335/ https://ncbi.nlm.nih.gov/pubmed/27473065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbw069 |
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