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APC Moonlights to Prevent Wnt Signalosome Assembly
The scaffold protein APC has a well-known function in ensuring β-catenin destruction. In this issue of Developmental Cell, Saito-Diaz et al. (2018) uncover another role for APC in Wnt signaling: to prevent clathrin-dependent signalosome formation in the absence of ligand.
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| Publicado en: | Dev Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cell Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5861992/ https://ncbi.nlm.nih.gov/pubmed/29533767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.02.018 |
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