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Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation

BACKGROUND: Apolipoprotein E (ApoE) is the major carrier protein that mediates the transport and delivery of cholesterol and other lipids in the brain. Three isoforms of ApoE (ApoE2, ApoE3, ApoE4) exist in humans, and their relative expression levels impact HIV-1 infection, HIV-1/AIDS disease progre...

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Pubblicato in:J Neuroinflammation
Autori principali: Khan, Nabab, Datta, Gaurav, Geiger, Jonathan D., Chen, Xuesong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861635/
https://ncbi.nlm.nih.gov/pubmed/29558961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1129-1
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