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Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation

BACKGROUND: Apolipoprotein E (ApoE) is the major carrier protein that mediates the transport and delivery of cholesterol and other lipids in the brain. Three isoforms of ApoE (ApoE2, ApoE3, ApoE4) exist in humans, and their relative expression levels impact HIV-1 infection, HIV-1/AIDS disease progre...

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Publicat a:J Neuroinflammation
Autors principals: Khan, Nabab, Datta, Gaurav, Geiger, Jonathan D., Chen, Xuesong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861635/
https://ncbi.nlm.nih.gov/pubmed/29558961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1129-1
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