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Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation

BACKGROUND: Apolipoprotein E (ApoE) is the major carrier protein that mediates the transport and delivery of cholesterol and other lipids in the brain. Three isoforms of ApoE (ApoE2, ApoE3, ApoE4) exist in humans, and their relative expression levels impact HIV-1 infection, HIV-1/AIDS disease progre...

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Bibliografiska uppgifter
I publikationen:J Neuroinflammation
Huvudupphovsmän: Khan, Nabab, Datta, Gaurav, Geiger, Jonathan D., Chen, Xuesong
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861635/
https://ncbi.nlm.nih.gov/pubmed/29558961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1129-1
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