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Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation

BACKGROUND: Apolipoprotein E (ApoE) is the major carrier protein that mediates the transport and delivery of cholesterol and other lipids in the brain. Three isoforms of ApoE (ApoE2, ApoE3, ApoE4) exist in humans, and their relative expression levels impact HIV-1 infection, HIV-1/AIDS disease progre...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Khan, Nabab, Datta, Gaurav, Geiger, Jonathan D., Chen, Xuesong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861635/
https://ncbi.nlm.nih.gov/pubmed/29558961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1129-1
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