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Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation
BACKGROUND: Apolipoprotein E (ApoE) is the major carrier protein that mediates the transport and delivery of cholesterol and other lipids in the brain. Three isoforms of ApoE (ApoE2, ApoE3, ApoE4) exist in humans, and their relative expression levels impact HIV-1 infection, HIV-1/AIDS disease progre...
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| Published in: | J Neuroinflammation |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5861635/ https://ncbi.nlm.nih.gov/pubmed/29558961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1129-1 |
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