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BK channels regulate extracellular Tat-mediated HIV-1 LTR transactivation

HIV-1 Tat is essential for HIV-1 replication and plays an important role in latent HIV-1 infection, HIV-1 associated neurological complication, and other HIV-1 comorbidities. Secreted from HIV-1 infected or transfected cells, Tat can be up-taken into cells by receptor-mediated endocytosis and intern...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Khan, Nabab, Lakpa, Koffi L., Halcrow, Peter W., Afghah, Zahra, Miller, Nicole M., Geiger, Jonathan D., Chen, Xuesong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706582/
https://ncbi.nlm.nih.gov/pubmed/31439883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48777-y
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