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High-Salt Intake Augments the Activity of the RhoA/ROCK Pathway and Reduces Intracellular Calcium in Arteries From Rats

BACKGROUND: We investigated the influence of salt overconsumption on the functionality of the RhoA/Rho-associated kinase (ROCK) pathway and calcium regulation in arteries. METHODS: The aorta and small mesenteric arteries from rats fed a chow containing 2%, 4%, or 8% NaCl were evaluated in organ bath...

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Pubblicato in:Am J Hypertens
Autori principali: Crestani, Sandra, Webb, Robert Clinton, da Silva-Santos, José Eduardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861573/
https://ncbi.nlm.nih.gov/pubmed/28164209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpw201
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