RAD51 and RTEL1 compensate telomere loss in the absence of telomerase

Replicative erosion of telomeres is naturally compensated by telomerase and studies in yeast and vertebrates show that homologous recombination can compensate for the absence of telomerase. We show that RAD51 protein, which catalyzes the key strand-invasion step of homologous recombination, is local...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Olivier, Margaux, Charbonnel, Cyril, Amiard, Simon, White, Charles I, Gallego, Maria E
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861403/
https://ncbi.nlm.nih.gov/pubmed/29346668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1322
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