Telomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner

The telomeres of linear eukaryotic chromosomes are protected by caps consisting of evolutionarily conserved nucleoprotein complexes. Telomere dysfunction leads to recombination of chromosome ends and this can result in fusions which initiate chromosomal breakage–fusion–bridge cycles, causing genomic...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Amiard, Simon, Olivier, Margaux, Allain, Elisabeth, Choi, Kyuha, Smith-Unna, Richard, Henderson, Ian R., White, Charles I., Gallego, Maria Eugenia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231758/
https://ncbi.nlm.nih.gov/pubmed/25274733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku897
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