SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis

Slit-Robo GTPase-activating protein 1 (SRGAP1) functions as a GAP for Rho-family GTPases and downstream of Slit-Robo signaling. We aim to investigate the biological function of SRGAP1 and reveal its regulation by deregulated microRNAs (miRNAs) in gastric cancer (GC). mRNA and protein expression of S...

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Udgivet i:Oncogene
Main Authors: Huang, Tingting, Zhou, Yuhang, Zhang, Jinglin, Wong, Chi Chun, Li, Weilin, Kwan, Johnny S. H., Yang, Rui, Chan, Aden K. Y., Dong, Yujuan, Wu, Feng, Zhang, Bin, Cheung, Alvin H. K., Wu, William K. K., Cheng, Alfred S. L., Yu, Jun, Wong, Nathalie, Kang, Wei, To, Ka Fai
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861093/
https://ncbi.nlm.nih.gov/pubmed/29234151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0029-7
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