NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway

Aberrant Notch activation has been implicated in multiple malignancies and the identification of NOTCH receptors and related pathways is critical for targeted therapy. In this study, we aim to delineate the most prominent dysregulated NOTCH receptor and comprehensively reveal its deregulation in gas...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Kang, Wei, Zhang, Jinglin, Huang, Tingting, Zhou, Yuhang, Wong, Chi Chun, Chan, Ronald C. K., Dong, Yujuan, Wu, Feng, Zhang, Bin, Wu, William K. K., Chan, Michael W. Y., Cheng, Alfred S. L., Yu, Jun, Wong, Nathalie, Lo, Kwok Wai, To, Ka Fai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932926/
https://ncbi.nlm.nih.gov/pubmed/33452458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01579-3
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