Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients—a Systematic Review

High-throughput sequencing analysis has accelerated searches for genes associated with risk for colorectal cancer (CRC); germline mutations in NTHL1, RPS20, FANCM, FAN1, TP53, BUB1, BUB3, LRP6, and PTPN12 have been recently proposed to increase CRC risk. We attempted to validate the association betw...

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發表在:Gastroenterology
Main Authors: Broderick, Peter, Dobbins, Sara E, Chubb, Daniel, Kinnersley, Ben, Dunlop, Malcolm G, Tomlinson, Ian, Houlston, Richard S
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860724/
https://ncbi.nlm.nih.gov/pubmed/27713038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.09.041
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