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Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes

Although family history is a major risk factor for colorectal cancer (CRC) a genetic diagnosis cannot be obtained in over 50 % of familial cases when screened for known CRC cancer susceptibility genes. The genetics of undefined-familial CRC is complex and recent studies have implied additional clini...

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Bibliografiska uppgifter
I publikationen:Fam Cancer
Huvudupphovsmän: Dobbins, Sara E., Broderick, Peter, Chubb, Daniel, Kinnersley, Ben, Sherborne, Amy L., Houlston, Richard S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Netherlands 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010824/
https://ncbi.nlm.nih.gov/pubmed/27356891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-016-9914-4
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