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Assessment of Hepatic Impairment and Implications for Pharmacokinetics of Substance Use Treatment
While the liver is the primary site of metabolism and biliary excretion for many medications, data are limited on the liver’s pharmacokinetic abilities in cirrhosis. Cirrhosis develops through collagen deposition eventually culminating in end-stage liver disease that compromises hepatic drug metabol...
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| 發表在: | Clin Pharmacol Drug Dev |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859945/ https://ncbi.nlm.nih.gov/pubmed/28263464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.336 |
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