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Assessment of Hepatic Impairment and Implications for Pharmacokinetics of Substance Use Treatment

While the liver is the primary site of metabolism and biliary excretion for many medications, data are limited on the liver’s pharmacokinetic abilities in cirrhosis. Cirrhosis develops through collagen deposition eventually culminating in end-stage liver disease that compromises hepatic drug metabol...

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Vydáno v:Clin Pharmacol Drug Dev
Hlavní autoři: Talal, Andrew H., Venuto, Charles S., Younis, Islam
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859945/
https://ncbi.nlm.nih.gov/pubmed/28263464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.336
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