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Assessment of Hepatic Impairment and Implications for Pharmacokinetics of Substance Use Treatment

While the liver is the primary site of metabolism and biliary excretion for many medications, data are limited on the liver’s pharmacokinetic abilities in cirrhosis. Cirrhosis develops through collagen deposition eventually culminating in end-stage liver disease that compromises hepatic drug metabol...

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Bibliografske podrobnosti
izdano v:Clin Pharmacol Drug Dev
Main Authors: Talal, Andrew H., Venuto, Charles S., Younis, Islam
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859945/
https://ncbi.nlm.nih.gov/pubmed/28263464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.336
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