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Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency
Unregulated, particularly suppressed programmed cell death is one of the distinguishing features of many cancer cells. The cysteine protease caspase-6, one of the executioners of apoptotic cell death, plays a crucial role in regulation of apoptosis. Several CASP6 gene somatic mutations in tumor tiss...
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| Publicado en: | Biochemistry |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859315/ https://ncbi.nlm.nih.gov/pubmed/28726391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00357 |
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