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Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells

Mutations in the human dynamin-related protein Drp1 cause mitochondria to form perinuclear clusters. We show here that these mitochondrial clusters consist of highly interconnected mitochondrial tubules. The increased connectivity between mitochondria indicates that the balance between mitochondrial...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Smirnova, Elena, Griparic, Lorena, Shurland, Dixie-Lee, van der Bliek, Alexander M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC58592/
https://ncbi.nlm.nih.gov/pubmed/11514614
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