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Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1
Balanced rates of mitochondrial division and fusion are required to maintain mitochondrial function, as well as cellular and organismal homeostasis. In mammals, the cellular machines that mediate these processes are dynamin-related GTPases; the cytosolic DRP1 mediates division, while the outer membr...
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| Publicat a: | Biochem Biophys Res Commun |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6626631/ https://ncbi.nlm.nih.gov/pubmed/29601815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.03.189 |
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