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Multiplexed imaging of high-density libraries of RNAs with MERFISH and expansion microscopy

As an image-based single-cell transcriptomics approach, multiplexed error-robust fluorescence in situ hybridization (MERFISH) allows hundreds to thousands of RNA species to be identified, counted and localized in individual cells while preserving the native spatial context of RNAs. In MERFISH, RNAs...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Wang, Guiping, Moffitt, Jeffrey R., Zhuang, Xiaowei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859009/
https://ncbi.nlm.nih.gov/pubmed/29555914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22297-7
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