GPR81, a cell-surface receptor for lactate, regulates intestinal homeostasis and protects mice from experimental colitis

At mucosal sites such as the intestine, the immune system launches robust immunity against invading pathogens while maintaining a state of tolerance to commensal flora and ingested food antigens. The molecular mechanisms underlying this phenomenon remain poorly understood. Here, we report that signa...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Ranganathan, Punithavathi, Shanmugam, Arulkumaran, Swafford, Daniel, Suryawanshi, Amol, Bhattacharjee, Pushpak, Hussein, Mohamed S, Koni, Pandelakis A, Prasad, Puttur D, Kurago, Zoya B, Thangaraju, Muthusamy, Ganapathy, Vadivel, Manicassamy, Santhakumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858928/
https://ncbi.nlm.nih.gov/pubmed/29386257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700604
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