Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

The tumor microenvironment (TME) contains high levels of the Wnt family of ligands, and aberrant Wnt-signaling occurs in many tumors. Past studies have been directed toward how the Wnt signaling cascade regulates cancer development, progression and metastasis. However, its effects on host antitumor...

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Vydáno v:Oncoimmunology
Hlavní autoři: Hong, Yuan, Manoharan, Indumathi, Suryawanshi, Amol, Shanmugam, Arulkumaran, Swafford, Daniel, Ahmad, Shamim, Chinnadurai, Raghavan, Manicassamy, Balaji, He, Yukai, Mellor, Andrew L., Thangaraju, Muthusamy, Munn, David H., Manicassamy, Santhakumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839371/
https://ncbi.nlm.nih.gov/pubmed/27141399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1115941
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