β-catenin promotes T regulatory cell responses in tumors by inducing vitamin A metabolism in dendritic cells

Tumors actively suppress antitumor immunity creating formidable barriers to successful cancer immunotherapy. The molecular mechanisms underlying tumor-induced immune tolerance are largely unknown. In the present study, we show that dendritic cells (DCs) in the tumor microenvironment (TME) acquire th...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Hong, Yuan, Manoharan, Indumathi, Suryawanshi, Amol, Majumdar, Tanmay, Angus-Hill, Melinda L., Koni, Pandelakis A., Manicassamy, Balaji, Mellor, Andrew L., Munn, David H., Manicassamy, Santhakumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333068/
https://ncbi.nlm.nih.gov/pubmed/25568183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2377
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