Endothelial dysfunction in pulmonary arterial hypertension: loss of cilia length regulation upon cytokine stimulation

Pulmonary arterial hypertension (PAH) is a syndrome characterized by progressive lung vascular remodelling, endothelial cell (EC) dysfunction, and excessive inflammation. The primary cilium is a sensory antenna that integrates signalling and fine tunes EC responses to various stimuli. Yet, cilia fun...

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Vydáno v:Pulm Circ
Hlavní autoři: Dummer, Anneloes, Rol, Nina, Szulcek, Robert, Kurakula, Kondababu, Pan, Xiaoke, Visser, Benjamin I., Bogaard, Harm Jan, DeRuiter, Marco C., Goumans, Marie-José, Hierck, Beerend P.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858634/
https://ncbi.nlm.nih.gov/pubmed/29480152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894018764629
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