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Thoracic Aortic Aneurysm Development in Patients with Bicuspid Aortic Valve: What Is the Role of Endothelial Cells?

Bicuspid aortic valve (BAV) is the most common type of congenital cardiac malformation. Patients with a BAV have a predisposition for the development of thoracic aortic aneurysm (TAA). This pathological aortic dilation may result in aortic rupture, which is fatal in most cases. The abnormal aortic m...

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Pubblicato in:Front Physiol
Autori principali: van de Pol, Vera, Kurakula, Kondababu, DeRuiter, Marco C., Goumans, Marie-José
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714935/
https://ncbi.nlm.nih.gov/pubmed/29249976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00938
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