Endothelial Colony Forming Cells as an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve

Bicuspid aortic valve (BAV), the most common congenital heart defect, is associated with an increased prevalence of aortic dilation, aortic rupture and aortic valve calcification. Endothelial cells (ECs) play a major role in vessel wall integrity. Little is known regarding EC function in BAV patient...

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Detalhes bibliográficos
Main Authors: Vera van de Pol, Lidia R. Bons, Kirsten Lodder, Konda Babu Kurakula, Gonzalo Sanchez-Duffhues, Hans-Marc J. Siebelink, Jolien W. Roos-Hesselink, Marco C. DeRuiter, Marie-José Goumans
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-07-01
Colecção:International Journal of Molecular Sciences
Assuntos:
endothelial colony forming cell
ECFC
blood outgrowth endothelial cell
BOEC
bicuspid aortic valve
BAV
aortic dilation
calcification
migration
Acesso em linha:https://www.mdpi.com/1422-0067/20/13/3251
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