DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages

Protein SUMOylation has been reported to play a role in innate immune response, but the enzymes, substrates, and consequences of the specific inflammatory signaling events are largely unknown. Reactive oxygen species (ROS) are abundantly produced during macrophage activation and required for Toll-li...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Lao, Yimin, Yang, Kai, Wang, Zhaojun, Sun, Xueqing, Zou, Qiang, Yu, Xiaoyan, Cheng, Jinke, Tong, Xuemei, Yeh, Edward T. H., Yang, Jie, Yi, Jing
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2018
Θέματα:
Immunology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857993/
https://ncbi.nlm.nih.gov/pubmed/29352108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.816769
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