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K(V)4.3 Expression Modulates Na(V)1.5 Sodium Current
In cardiomyocytes, the voltage-gated transient outward potassium current (I(to)) is responsible for the phase-1 repolarization of the action potential (AP). Gain-of-function mutations in KCND3, the gene encoding the I(to) carrying K(V)4.3 channel, have been associated with Brugada syndrome (BrS). Wh...
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| Publicado no: | Front Physiol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5857579/ https://ncbi.nlm.nih.gov/pubmed/29593552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00178 |
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