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The sodium channel Na(V)1.5 impacts on early murine embryonic cardiac development, structure and function in a non‐electrogenic manner
AIM: The voltage‐gated sodium channel Na(V)1.5, encoded by SCN5A, is essential for cardiac excitability and ensures proper electrical conduction. Early embryonic death has been observed in several murine models carrying homozygous Scn5amutations. We investigated when sodium current (I(Na)) becomes f...
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| Publicado no: | Acta Physiol (Oxf) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7539970/ https://ncbi.nlm.nih.gov/pubmed/32386467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13493 |
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