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Recent Mass Spectrometry-based Techniques and Considerations for Disulfide Bond Characterization in Proteins

Disulfide bonds are important structural moieties of proteins; they ensure proper folding, provide stability, and proper function. With the increasing use of proteins for biotherapeutics, particularly monoclonal antibodies, which are highly disulfide bonded, it is now important to confirm the correc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Bioanal Chem
Prif Awduron: Lakbub, Jude C., Shipman, Joshua T., Desaire, Heather
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857437/
https://ncbi.nlm.nih.gov/pubmed/29256076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-017-0772-1
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