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Recent Mass Spectrometry-based Techniques and Considerations for Disulfide Bond Characterization in Proteins

Disulfide bonds are important structural moieties of proteins; they ensure proper folding, provide stability, and proper function. With the increasing use of proteins for biotherapeutics, particularly monoclonal antibodies, which are highly disulfide bonded, it is now important to confirm the correc...

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Bibliografiske detaljer
Udgivet i:Anal Bioanal Chem
Main Authors: Lakbub, Jude C., Shipman, Joshua T., Desaire, Heather
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857437/
https://ncbi.nlm.nih.gov/pubmed/29256076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-017-0772-1
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