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Regulatory dynamics determine cell fate following abrupt antibiotic exposure

Bacterial resistance mechanisms must cope with transient fast-changing conditions. These systems are often repressed in absence of the drug and it is unclear how their regulation can provide a quick response when challenged. Here we focus on the tet operon, which provides resistance to tetracycline...

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Библиографические подробности
Опубликовано в: :Cell Syst
Главные авторы: Schultz, Daniel, Palmer, Adam C., Kishony, Roy
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857293/
https://ncbi.nlm.nih.gov/pubmed/29102611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.10.002
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