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Chemical decay of an antibiotic inverts selection for resistance

Antibiotics are often unstable, decaying into various compounds with potential biological activities. We found that as tetracycline degrades, the competitive advantage conferred to bacteria by resistance not only diminishes, but reverses to become a prolonged disadvantage due to the activities of mo...

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Bibliografiska uppgifter
Huvudupphovsmän: Palmer, Adam C., Angelino, Elaine, Kishony, Roy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811317/
https://ncbi.nlm.nih.gov/pubmed/20081825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.289
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