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Chemical decay of an antibiotic inverts selection for resistance
Antibiotics are often unstable, decaying into various compounds with potential biological activities. We found that as tetracycline degrades, the competitive advantage conferred to bacteria by resistance not only diminishes, but reverses to become a prolonged disadvantage due to the activities of mo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811317/ https://ncbi.nlm.nih.gov/pubmed/20081825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.289 |
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