A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus Following Pediatric Renal Transplantation

BACKGROUND: Multiple clinical, demographic, and genetic factors affect the pharmacokinetics of tacrolimus in children, yet in daily practice, a uniform body-weight based starting dose is used. It can take weeks to reach the target tacrolimus pre-dose concentration. OBJECTIVES: The objectives of this...

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Detaylı Bibliyografya
Yayımlandı:Clin Pharmacokinet
Asıl Yazarlar: Andrews, Louise M., Hesselink, Dennis A., van Gelder, Teun, Koch, Birgit C. P., Cornelissen, Elisabeth A. M., Brüggemann, Roger J. M., van Schaik, Ron H. N., de Wildt, Saskia N., Cransberg, Karlien, de Winter, Brenda C. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2017
Konular:
Original Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856873/
https://ncbi.nlm.nih.gov/pubmed/28681225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0567-8
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