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T(reg) cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration

Skeletal muscle regeneration is a highly orchestrated process that depends on multiple immune-system cell types, notably macrophages (MFs) and Foxp3(+)CD4(+) regulatory T (T(reg)) cells. This study addressed how T(reg) cells rein in MFs during regeneration of murine muscle after acute injury with ca...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Panduro, Marisella, Benoist, Christophe, Mathis, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856564/
https://ncbi.nlm.nih.gov/pubmed/29476012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800618115
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