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T cell anergy in perinatal mice is promoted by T reg cells and prevented by IL-33

Perinatal T cells broadly access nonlymphoid tissues, where they are exposed to sessile tissue antigens. To probe the outcome of such encounters, we examined the defective elimination of self-reactive clones in Aire-deficient mice. Nonlymphoid tissues were sequentially seeded by distinct waves of CD...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Tuncel, Jonatan, Benoist, Christophe, Mathis, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547863/
https://ncbi.nlm.nih.gov/pubmed/30988052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182002
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