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T cell anergy in perinatal mice is promoted by T reg cells and prevented by IL-33
Perinatal T cells broadly access nonlymphoid tissues, where they are exposed to sessile tissue antigens. To probe the outcome of such encounters, we examined the defective elimination of self-reactive clones in Aire-deficient mice. Nonlymphoid tissues were sequentially seeded by distinct waves of CD...
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| Publicado en: | J Exp Med |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547863/ https://ncbi.nlm.nih.gov/pubmed/30988052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182002 |
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