Appearance and disappearance of the mRNA signature characteristic of T(reg) cells in visceral adipose tissue: Age, diet, and PPARγ effects

A unique population of Foxp3(+)CD4(+) regulatory T (T(reg)) cells resides in visceral adipose tissue (VAT) of lean mice, especially in the epididymal fat depot. VAT T(regs) are unusual in their very high representation within the CD4(+) T-cell compartment, their transcriptome, and their repertoire o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cipolletta, Daniela, Cohen, Paul, Spiegelman, Bruce M., Benoist, Christophe, Mathis, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299242/
https://ncbi.nlm.nih.gov/pubmed/25550516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423486112
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