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Reconstitution of S. aureus lipoteichoic acid synthase activity identifies Congo red as a selective inhibitor
Lipoteichoic acid (LTA) is an anionic surface pol-ymer that is essential for normal growth of Staphylococcus aureus, making the LTA polymerase, LTA synthase (LtaS), a proposed drug target for combating Staphylococcal infections. LtaS is a polytopic membrane protein with five membrane-spanning helice...
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| Publicado no: | J Am Chem Soc |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856125/ https://ncbi.nlm.nih.gov/pubmed/29300473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11704 |
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