A partial reconstitution implicates DltD in catalyzing lipoteichoic acid d-alanylation

Modifications to the Gram-positive bacterial cell wall play important roles in antibiotic resistance and pathogenesis, but the pathway for the d-alanylation of teichoic acids (DLT pathway), a ubiquitous modification, is poorly understood. The d-alanylation machinery includes two membrane proteins of...

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Udgivet i:J Biol Chem
Main Authors: Wood, B. McKay, Santa Maria, John P., Matano, Leigh M., Vickery, Christopher R., Walker, Suzanne
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240853/
https://ncbi.nlm.nih.gov/pubmed/30237166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004561
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