Proteolytic Cleavage Inactivates the Staphylococcus aureus Lipoteichoic Acid Synthase

Lipoteichoic acid (LTA) is a crucial cell envelope component in Gram-positive bacteria. In Staphylococcus aureus, the polyglycerolphosphate LTA molecule is synthesized by LtaS, a membrane-embedded enzyme with five N-terminal transmembrane helices (5TM domain) that are connected via a linker region t...

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Bibliographic Details
Main Authors: Wörmann, Mirka E., Reichmann, Nathalie T., Malone, Cheryl L., Horswill, Alexander R., Gründling, Angelika
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Microbial Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187375/
https://ncbi.nlm.nih.gov/pubmed/21784926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00369-11
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