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Allele-specific SHAPE-MaP assessment of the effects of somatic variation and protein binding on mRNA structure
The impact of inherited and somatic mutations on messenger RNA (mRNA) structure remains poorly understood. Recent technological advances that leverage next-generation sequencing to obtain experimental structure data, such as SHAPE-MaP, can reveal structural effects of mutations, especially when thes...
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| Publicado no: | RNA |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5855952/ https://ncbi.nlm.nih.gov/pubmed/29317542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064469.117 |
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