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Allele-specific SHAPE-MaP assessment of the effects of somatic variation and protein binding on mRNA structure

The impact of inherited and somatic mutations on messenger RNA (mRNA) structure remains poorly understood. Recent technological advances that leverage next-generation sequencing to obtain experimental structure data, such as SHAPE-MaP, can reveal structural effects of mutations, especially when thes...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA
Egile Nagusiak: Lackey, Lela, Coria, Aaztli, Woods, Chanin, McArthur, Evonne, Laederach, Alain
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855952/
https://ncbi.nlm.nih.gov/pubmed/29317542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064469.117
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